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When James Lacy was growing up, his father prospered by running a general store in rural Texas. But the merchant lost everything in the economic collapse of 1929. Though his dad spent decades paying off debts, Lacy says, he was rich in other ways.

NPR's Juana Summers talks with Dr. Anthony Fauci about the Biden administration's response to the monkeypox outbreak and the current COVID-19 omicron variant surge.

Thousands of people were expected in Las Vegas for the first weekend of NCAA men's college basketball tournament. It's one of the most lucrative weekends in Las Vegas. Casino officials say it draws more people than the Super Bowl.

Residents of the west coast of Mexico are assessing the damage from Hurricane Patricia on Saturday. The storm hit late Friday night but lost some of its record-breaking strength as it made landfall.

Conductor John Eliot Gardiner and author Matthew Guerrieri explain the incredible resonances, past and present, behind one of the most famous phrases in music: the start to Beethoven's Fifth Symphony.

Washington Post reporter Wesley Lowery talks about race in the Obama presidency and under President-elect Trump. Lowery was part of a Pulitzer Prize-winning team for reporting about police shootings.

When it comes to learning an instrument, children have the edge in many respects. Using himself as a guinea pig, psychology professor Gary Marcus resolved to find out whether nonmusical adults have any chance of turning things around.

Every winter, people camp out for days in a parking lot in western Alaska to get permits to hunt muskox. It's kind of a big deal.

An experimental COVID-19 medicine that has been shown to shorten the time people with severe illness have to stay in the hospital finally has a price tag that's lower than some analysts expected.

NPR's Steve Inskeep talks to economist Douglas Holtz-Eakin, who served in the George W. Bush White House, and led the nonpartisan congressional budget office, about how the proposal is being received.